{"id":16992,"date":"2019-11-15T07:41:38","date_gmt":"2019-11-15T07:41:38","guid":{"rendered":"https:\/\/www.revoscience.com\/en\/?p=16992"},"modified":"2020-10-02T21:45:43","modified_gmt":"2020-10-02T16:00:43","slug":"researchers-reveal-for-safer-mri-treatment","status":"publish","type":"post","link":"https:\/\/www.revoscience.com\/en\/researchers-reveal-for-safer-mri-treatment\/","title":{"rendered":"Researchers reveal safer MRI treatment"},"content":{"rendered":"\n
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Photo Credit: NYU<\/em><\/figcaption><\/figure>\n\n\n\n

A new study suggests that a contrast agen<\/a>t in an MRI brightens the images could lead early detection of Cancer.<\/p>\n\n\n\n

Doctors are using Magnetic resonance imaging (MRI)<\/a> for medical diagnostics and monitoring therapeutic progress. But researchers alert for safety concerns about a substance are used during the MRI.<\/p>\n\n\n\n

Ramesh Marasini, a PhD Candidate for Kansas State University\u2019s Department of Chemistry<\/a> has said, “not only cancer, cardiovascular disease, or problems in the muscles or bone could be detected with extreme precision using much lower drug dose than existing contrast media,\u201d <\/p>\n\n\n\n

According to United States Food and Drug Administration, a contrast agent is\nharmful for human body and health. <\/p>\n\n\n\n

If released from the chelating agent, these ions are toxic to vital organs including the kidney, brain, and bone. It has been reported that about 40% of MRI scans use GBCAs globally, which accounts for about 50 tons of gadolinium injected annually for clinical investigations, reported in Advanced Science News<\/a>.<\/p>\n\n\n\n

This imaging technique is further enhanced by the use of\ngadolinium-based contrast agents (GBCAs) in which a gadolinium ion is enclosed\nin the chelating agent, which acts as an umbrella to protect ions from being\nprematurely released.<\/p>\n\n\n\n

\u201cDue to huge toxicity most of them are already banned in the E.U,\u201d said Dr. Santosh Aryal, a K-State Assistant Professor of Chemistry. <\/p>\n\n\n\n

Toward this endeavor, Ramesh Marasini, Tuyen Nguyen, and Santosh\nAryal, of Kansas State University, discuss strategically designed\nnanoscale GBCAs for MRI<\/a> with the goal to achieve improved\ncontrast enhancement and safety profile.<\/p>\n\n\n\n

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Photo credit: Advanced Science News<\/em><\/figcaption><\/figure>\n\n\n\n

The main benefits of using nanoscale contrast\nmedia are to provide a large contrast difference between tissues of interest\nand normal tissues by localizing the contrast agent and minimizing the\ngadolinium dose. Therefore, the research and development of nanoscale contrast\nformulations with unique properties have continued to expand.<\/p>\n\n\n\n

The next steps for the\nresearch team are animal trials, followed by clinical trials with people.<\/p>\n\n\n\n

According to Marasini, it will take 3-4 years that we could plan for animal clinical trials.” The aim of research is medically advancements could make MRI\u2019s safer in the future.<\/p>\n\n\n

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