{"id":25568,"date":"2024-12-15T22:37:48","date_gmt":"2024-12-15T16:52:48","guid":{"rendered":"https:\/\/www.revoscience.com\/en\/?p=25568"},"modified":"2024-12-15T22:37:51","modified_gmt":"2024-12-15T16:52:51","slug":"ugh-my-stomach-identifying-amino-acids-that-prevent-sporulation-in-food-poisoning","status":"publish","type":"post","link":"https:\/\/www.revoscience.com\/en\/ugh-my-stomach-identifying-amino-acids-that-prevent-sporulation-in-food-poisoning\/","title":{"rendered":"Ugh, my stomach: Identifying amino acids that prevent sporulation in food poisoning"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"675\" height=\"442\" sizes=\"auto, (max-width: 675px) 100vw, 675px\" src=\"https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-675x442.jpg\" alt=\"\" class=\"wp-image-25569\" style=\"width:840px;height:auto\" title=\"\" srcset=\"https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-675x442.jpg 675w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-610x400.jpg 610w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-768x503.jpg 768w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-870x570.jpg 870w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-550x360.jpg 550w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens.jpg 1045w\" \/><\/figure>\n\n\n\n<p>Food poisoning is a common, yet unpleasant, illness caused by eating contaminated items. It is sometimes caused by&nbsp;<em>Clostridium perfringens,<\/em>&nbsp;a pathogen widely found in soil and the intestinal tracts of animals.<\/p>\n\n\n\n<p>The pathogen multiplies in environments with little oxygen, for example, curry stored in a pot. After ingestion of the pathogen, they form spores in the small intestinal tracts. The toxins produced during spore formation cause diarrhea and abdominal pain, but the underlying mechanism of spore formation has not been fully understood.<\/p>\n\n\n\n<p>Associate Professor Mayo Yasugi\u2019s team at Osaka Metropolitan University\u2019s Graduate School of Veterinary Science has examined how amino acids are involved in&nbsp;<em>Clostridium perfringens<\/em>&nbsp;spore formation. In this study, they created 21 culture mediums, 20 of which were each deprived of one of the amino acids that make proteins in the human body, to evaluate the pathogen\u2019s development.<\/p>\n\n\n\n<p>As a result, the team identified serine as an inhibitor of&nbsp;<em>Clostridium perfringens<\/em>&nbsp;spore formation. When observed under a microscope, it was found that serine inhibits the pathogen\u2019s cell wall from remodeling, which is necessary in the process of becoming a spore.&nbsp;<\/p>\n\n\n\n<p>\u201cThis is the first reported case where a single amino acid inhibits spore-forming anaerobic bacteria,\u201d stated Professor Yasugi. \u201cIn the future, we hope to understand serine inhibition, the pathogenic mechanisms of&nbsp;<em>Clostridium perfringens&nbsp;<\/em>food poisoning, and the survival strategies of pathogenic microorganisms in the human body. Hopefully, this will lead to academic contributions to microbiology and infectious diseases.\u201d<\/p>\n\n\n\n<p>The findings were published in&nbsp;<em>Anaerobe<\/em>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Food poisoning is a common, yet unpleasant, illness caused by eating contaminated items. <\/p>\n","protected":false},"author":2,"featured_media":25569,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17,16],"tags":[],"class_list":["post-25568","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","category-biology"],"featured_image_urls":{"full":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens.jpg",1045,685,false],"thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-200x200.jpg",200,200,true],"medium":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-610x400.jpg",610,400,true],"medium_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-768x503.jpg",750,491,true],"large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-675x442.jpg",675,442,true],"1536x1536":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens.jpg",1045,685,false],"2048x2048":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens.jpg",1045,685,false],"ultp_layout_landscape_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens.jpg",1045,685,false],"ultp_layout_landscape":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-870x570.jpg",870,570,true],"ultp_layout_portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-600x685.jpg",600,685,true],"ultp_layout_square":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-600x600.jpg",600,600,true],"newspaper-x-single-post":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-760x490.jpg",760,490,true],"newspaper-x-recent-post-big":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-550x360.jpg",550,360,true],"newspaper-x-recent-post-list-image":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens-95x65.jpg",95,65,true],"web-stories-poster-portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens.jpg",640,420,false],"web-stories-publisher-logo":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens.jpg",96,63,false],"web-stories-thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2024\/12\/Clostridium-perfringens.jpg",150,98,false]},"author_info":{"info":["RevoScience"]},"category_info":"<a href=\"https:\/\/www.revoscience.com\/en\/category\/news\/research\/\" rel=\"category tag\">Research<\/a> <a href=\"https:\/\/www.revoscience.com\/en\/category\/news\/biology\/\" rel=\"category tag\">Biology<\/a>","tag_info":"Biology","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/25568","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/comments?post=25568"}],"version-history":[{"count":1,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/25568\/revisions"}],"predecessor-version":[{"id":25570,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/25568\/revisions\/25570"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media\/25569"}],"wp:attachment":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media?parent=25568"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/categories?post=25568"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/tags?post=25568"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}