{"id":25715,"date":"2025-03-06T11:48:02","date_gmt":"2025-03-06T06:03:02","guid":{"rendered":"https:\/\/www.revoscience.com\/en\/?p=25715"},"modified":"2025-03-06T11:48:05","modified_gmt":"2025-03-06T06:03:05","slug":"motion-capture-in-world-1st-m-mobiles-motility-apparatus-clarified","status":"publish","type":"post","link":"https:\/\/www.revoscience.com\/en\/motion-capture-in-world-1st-m-mobiles-motility-apparatus-clarified\/","title":{"rendered":"Motion capture: In world 1st, M. mobile\u2019s motility apparatus clarified"},"content":{"rendered":"\n<p><strong><\/strong><strong><em>Cryo-electron microscopy reveals molecular structure of twin motors that power mycoplasma\u2019s ability to glide<\/em><\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"675\" height=\"521\" sizes=\"auto, (max-width: 675px) 100vw, 675px\" src=\"https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile-675x521.jpg\" alt=\"\" class=\"wp-image-25716\" style=\"width:840px;height:auto\" title=\"\" srcset=\"https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile-675x521.jpg 675w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile-518x400.jpg 518w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile.jpg 738w\" \/><\/figure>\n\n\n\n<p>Mycoplasmas, including bacteria that cause pneumonia in humans, are generally nonmotile, but\u00a0<em>Mycoplasma mobile<\/em>, as the species name suggests, has been found in the gills of fish and seems to move by gliding along surfaces. <\/p>\n\n\n\n<p>The molecular structure that allows it to do so has for the first time been uncovered by a collaborative research group led by Osaka Metropolitan University Professor Makoto Miyata of the Graduate School of Science.<\/p>\n\n\n\n<p>The OMU-led research team has been working since 1997 to clarify&nbsp;<em>M. mobile<\/em>\u2019s motility mechanisms. This time, with the help of Osaka University\u2019s cryo-electron microscopy equipment, the scientists revealed at near-atomic resolution the enzymes known as ATPases that use rotational catalytic mechanisms to power the gliding machinery.<\/p>\n\n\n\n<p>In addition, although the molecular structures of the two units that make up the twin motor are similar to those of known ATP synthases, the researchers found that they combine to form an unprecedented complex structure.<\/p>\n\n\n\n<p>\u201cThis achievement will promote further understanding of the motility mechanism of how the energy of ATP hydrolysis is converted into gliding motility, and how these motors of\u00a0<em>Mycoplasma mobile<\/em>\u00a0are thought to have evolved from ATP synthase,\u201d Professor Miyata explained.<\/p>\n\n\n\n<p>\u201cGoing forward, we can expect our results to be used as a basis for applications in nanobot actuators and for the development of medicines to fight mycoplasma infections.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cryo-electron microscopy reveals molecular structure of twin motors that power mycoplasma\u2019s ability to glide<\/p>\n","protected":false},"author":2,"featured_media":25716,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17,6],"tags":[],"class_list":["post-25715","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","category-health"],"featured_image_urls":{"full":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile.jpg",738,570,false],"thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile-200x200.jpg",200,200,true],"medium":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile-518x400.jpg",518,400,true],"medium_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile.jpg",738,570,false],"large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile-675x521.jpg",675,521,true],"1536x1536":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile.jpg",738,570,false],"2048x2048":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile.jpg",738,570,false],"ultp_layout_landscape_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile.jpg",738,570,false],"ultp_layout_landscape":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile.jpg",738,570,false],"ultp_layout_portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile-600x570.jpg",600,570,true],"ultp_layout_square":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile-600x570.jpg",600,570,true],"newspaper-x-single-post":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile-738x490.jpg",738,490,true],"newspaper-x-recent-post-big":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile-550x360.jpg",550,360,true],"newspaper-x-recent-post-list-image":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile-95x65.jpg",95,65,true],"web-stories-poster-portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile.jpg",640,494,false],"web-stories-publisher-logo":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile.jpg",96,74,false],"web-stories-thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/03\/Mycoplasma-mobile.jpg",150,116,false]},"author_info":{"info":["RevoScience"]},"category_info":"<a href=\"https:\/\/www.revoscience.com\/en\/category\/news\/research\/\" rel=\"category tag\">Research<\/a> <a href=\"https:\/\/www.revoscience.com\/en\/category\/health\/\" rel=\"category tag\">Health<\/a>","tag_info":"Health","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/25715","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/comments?post=25715"}],"version-history":[{"count":2,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/25715\/revisions"}],"predecessor-version":[{"id":25718,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/25715\/revisions\/25718"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media\/25716"}],"wp:attachment":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media?parent=25715"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/categories?post=25715"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/tags?post=25715"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}