{"id":25846,"date":"2025-04-12T12:56:56","date_gmt":"2025-04-12T07:11:56","guid":{"rendered":"https:\/\/www.revoscience.com\/en\/?p=25846"},"modified":"2025-04-12T12:56:58","modified_gmt":"2025-04-12T07:11:58","slug":"3d-raman-imaging-reveals-co2-reduction-inside-living-cells","status":"publish","type":"post","link":"https:\/\/www.revoscience.com\/en\/3d-raman-imaging-reveals-co2-reduction-inside-living-cells\/","title":{"rendered":"3D Raman Imaging Reveals CO2 Reduction Inside Living Cells"},"content":{"rendered":"\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"589\" height=\"529\" sizes=\"auto, (max-width: 589px) 100vw, 589px\" src=\"https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg\" alt=\"\" class=\"wp-image-25847\" style=\"width:840px;height:auto\" title=\"\" srcset=\"https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg 589w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing-445x400.jpg 445w\" \/><\/figure>\n\n\n\n<p>Researchers from National Taiwan University and collaborators have developed a novel way to observe and monitor carbon dioxide (CO<sub>2<\/sub>) conversion into carbon monoxide (CO) inside living cells, using an advanced optical method called surface-enhanced Raman spectroscopy (SERS).&nbsp;<\/p>\n\n\n\n<p>By designing special gold nanoflowers decorated with rhenium complexes (<a href=\"mailto:Re@Au\">Re@Au<\/a>), the team created a nanocatalyst that can reduce CO<sub>2<\/sub>\u00a0to CO within nerve cells. These nanostructures not only speed up the reaction but also enhance the Raman signal, allowing scientists to &#8220;see&#8221; the reaction happening in real-time. <\/p>\n\n\n\n<p>Importantly, this was achieved using 3D Raman imaging, a non-invasive method that provides detailed, spatial insights into the chemical reactions occurring within live cells.\u00a0<\/p>\n\n\n\n<p>Their study revealed that upon light irradiation, the&nbsp;<a href=\"mailto:Re@Au\">Re@Au<\/a>&nbsp;nanocatalysts convert CO<sub>2<\/sub>&nbsp;into CO with high selectivity, without harmful byproducts. Notably, the CO produced inside the cells was shown to promote neurite growth and reduce amyloid-beta protein levels \u2014 two effects relevant to treating neurodegenerative conditions like Alzheimer\u2019s disease.&nbsp;<\/p>\n\n\n\n<p>This pioneering work demonstrates how molecular reactions can be visualized in their natural cellular environment. By combining nanotechnology, photochemistry, and biomedical imaging, the study opens new doors for developing light-controlled therapies based on gas molecules like CO.&nbsp;<\/p>\n\n\n\n<p>\u201cWe hope this research paves the way for future catalytic therapies that can be precisely activated inside the human body,\u201d said Prof. Kien Voon Kong.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers from National Taiwan University and collaborators have developed a novel way to observe and monitor carbon dioxide (CO2) conversion into carbon monoxide (CO) inside living cells<\/p>\n","protected":false},"author":2,"featured_media":25847,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,17],"tags":[],"class_list":["post-25846","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","category-research"],"featured_image_urls":{"full":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg",589,529,false],"thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing-200x200.jpg",200,200,true],"medium":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing-445x400.jpg",445,400,true],"medium_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg",589,529,false],"large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg",589,529,false],"1536x1536":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg",589,529,false],"2048x2048":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg",589,529,false],"ultp_layout_landscape_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg",589,529,false],"ultp_layout_landscape":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg",589,529,false],"ultp_layout_portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg",589,529,false],"ultp_layout_square":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg",589,529,false],"newspaper-x-single-post":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing-589x490.jpg",589,490,true],"newspaper-x-recent-post-big":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing-550x360.jpg",550,360,true],"newspaper-x-recent-post-list-image":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing-95x65.jpg",95,65,true],"web-stories-poster-portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg",589,529,false],"web-stories-publisher-logo":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg",96,86,false],"web-stories-thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/04\/3d-raman-imazing.jpg",150,135,false]},"author_info":{"info":["RevoScience"]},"category_info":"<a href=\"https:\/\/www.revoscience.com\/en\/category\/health\/\" rel=\"category tag\">Health<\/a> <a href=\"https:\/\/www.revoscience.com\/en\/category\/news\/research\/\" rel=\"category tag\">Research<\/a>","tag_info":"Research","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/25846","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/comments?post=25846"}],"version-history":[{"count":1,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/25846\/revisions"}],"predecessor-version":[{"id":25848,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/25846\/revisions\/25848"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media\/25847"}],"wp:attachment":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media?parent=25846"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/categories?post=25846"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/tags?post=25846"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}