{"id":26799,"date":"2025-07-01T12:22:26","date_gmt":"2025-07-01T06:37:26","guid":{"rendered":"https:\/\/www.revoscience.com\/en\/?p=26799"},"modified":"2025-07-01T12:22:31","modified_gmt":"2025-07-01T06:37:31","slug":"a-small-reaction-space-has-a-big-impact-on-polymer-chemistry","status":"publish","type":"post","link":"https:\/\/www.revoscience.com\/en\/a-small-reaction-space-has-a-big-impact-on-polymer-chemistry\/","title":{"rendered":"A small reaction space has a big impact on polymer chemistry"},"content":{"rendered":"\n
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Tokyo, Japan\u2014 Mimicking the incredible skill of Mother Nature is never easy, especially when trying to match the remarkable chemical processes that take place in living organisms. <\/p>\n\n\n\n

Living systems, like cells, can carry out chemical reactions in very small spaces, sometimes involving single molecules. For many years, researchers have attempted to emulate this to allow for the manufacturing of specialized chemical compounds, but with limited success.<\/p>\n\n\n\n

However, new research published in the\u00a0Journal of the American Chemical Society<\/a><\/em>\u00a0highlights the development of a new tool that assists with controlling chemical reactions. This could allow important polymers\u2014the large, chainlike molecules with many modern applications\u2014to be created in incredibly small spaces with a high level of precision.<\/p>\n\n\n\n

The team, based at the Institute of Industrial Science, The University of Tokyo, developed a \u2018molecular flask\u2019\u2014which modulates the reactivity of the reactions happening in its interior\u2014using a carefully constructed single polymer molecule with a unique shape.<\/p>\n\n\n\n

\u201cPrevious work in this field has created small molecular reactors based on various porous materials,\u201d says lead author Xiangyuan Guo. \u201cHowever, it is difficult to use these processes to make specific polymers, because the polymerization reaction is not easily controlled.\u201d<\/p>\n\n\n\n

This new work created polymers based on central, wormlike molecules with many protruding side chains, known as a \u2018bottlebrush\u2019 shape. The side chains act to produce a kind of internal buffer zone that allows some substances to enter the space around the body of the polymer molecule while keeping others out.<\/p>\n\n\n\n

This zone can be as small as a single molecule and can be tailored to provide adequate space for the formation of other polymers. Inside these nanosized pockets, chemicals can react to produce only certain desired products, protected from the effects of their surroundings. For this reason, materials that are otherwise difficult to synthesize can be obtained using this system.<\/p>\n\n\n\n

\u201cOne of the main advantages of this new process is that it is extremely versatile,\u201d explains senior author Shintaro Nakagawa. \u201cThis was demonstrated by synthesizing two completely different types of polymers, including a specialized conjugated polymer based on thiophene with applications in optoelectronics.\u201d<\/p>\n\n\n\n

The spaces inside these carefully designed bottlebrush polymers are extremely small: on the order of tens of nanometers, meaning billionths of a meter. Similar to biological systems such as enzymes, these molecular-scale flasks allow an extreme level of control of chemical reactions.<\/p>\n\n\n\n

In addition to making specialty polymers with many different applications, this breakthrough technology could someday be employed to produce nanoparticles and other materials with applications in medicine, sensing technology, and other fields.<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

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