{"id":30604,"date":"2025-10-28T13:37:01","date_gmt":"2025-10-28T07:52:01","guid":{"rendered":"https:\/\/www.revoscience.com\/en\/?p=30604"},"modified":"2025-10-28T13:37:06","modified_gmt":"2025-10-28T07:52:06","slug":"new-drug-shows-promise-in-fighting-prostate-cancer","status":"publish","type":"post","link":"https:\/\/www.revoscience.com\/en\/new-drug-shows-promise-in-fighting-prostate-cancer\/","title":{"rendered":"New Drug Shows Promise in Fighting Prostate Cancer"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

Ann Arbor, MI \u2014<\/strong> Researchers at the University of Michigan have discovered a new way to stop the growth of prostate cancer using a targeted drug called CBPD-409.<\/p>\n\n\n\n

Prostate cancer cells rely on certain proteins\u2014p300 and CBP\u2014to activate genes that help tumors grow. The research team found that these proteins also add a chemical marker called H2BNTac, which plays a key role in cancer development.<\/p>\n\n\n\n

The new drug, CBPD-409, works by breaking down p300 and CBP, removing the H2BNTac marker, and shutting down the cancer-driving signals. It can be taken orally and has shown strong results in lab tests, including shrinking tumors in advanced prostate cancer models.<\/p>\n\n\n\n

\u201cThis drug could be especially effective for patients whose cancer cells have high levels of H2BNTac,\u201d said lead researcher Dr. Arul Chinnaiyan.<\/p>\n\n\n\n

The study was published in Nature Genetics<\/em> and highlights a new approach to treating castration-resistant prostate cancer, a form of the disease that no longer responds to hormone therapy.<\/p>\n\n\n\n

Prostate cancer is the most common cancer in men in the U.S. and a major cause of cancer-related deaths. Scientists hope this breakthrough will lead to better treatments in the near future.<\/p>\n","protected":false},"excerpt":{"rendered":"

Ann Arbor, MI \u2014 Researchers at the University of Michigan have discovered a new way to stop the growth of prostate cancer using a targeted drug called CBPD-409.<\/p>\n","protected":false},"author":2,"featured_media":30605,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-30604","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"featured_image_urls":{"full":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer.webp",640,640,false],"thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer-200x200.webp",200,200,true],"medium":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer.webp",640,640,false],"medium_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer.webp",640,640,false],"large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer.webp",640,640,false],"1536x1536":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer.webp",640,640,false],"2048x2048":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer.webp",640,640,false],"ultp_layout_landscape_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer.webp",640,640,false],"ultp_layout_landscape":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer-640x570.webp",640,570,true],"ultp_layout_portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer-600x640.webp",600,640,true],"ultp_layout_square":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer-600x600.webp",600,600,true],"newspaper-x-single-post":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer-640x490.webp",640,490,true],"newspaper-x-recent-post-big":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer-550x360.webp",550,360,true],"newspaper-x-recent-post-list-image":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer-95x65.webp",95,65,true],"web-stories-poster-portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer.webp",640,640,false],"web-stories-publisher-logo":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer-96x96.webp",96,96,true],"web-stories-thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2025\/10\/Prostate-Cancer-150x150.webp",150,150,true]},"author_info":{"info":["RevoScience"]},"category_info":"Health<\/a>","tag_info":"Health","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/30604","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/comments?post=30604"}],"version-history":[{"count":1,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/30604\/revisions"}],"predecessor-version":[{"id":30606,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/30604\/revisions\/30606"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media\/30605"}],"wp:attachment":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media?parent=30604"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/categories?post=30604"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/tags?post=30604"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}