{"id":35866,"date":"2026-02-23T16:19:20","date_gmt":"2026-02-23T10:34:20","guid":{"rendered":"https:\/\/www.revoscience.com\/en\/?p=35866"},"modified":"2026-02-23T16:19:22","modified_gmt":"2026-02-23T10:34:22","slug":"oman-researchers-find-camel-peptides-with-promise-against-drug-resistant-bacteria","status":"publish","type":"post","link":"https:\/\/www.revoscience.com\/en\/oman-researchers-find-camel-peptides-with-promise-against-drug-resistant-bacteria\/","title":{"rendered":"Oman researchers find camel peptides with promise against drug-resistant bacteria"},"content":{"rendered":"\n<figure class=\"wp-block-image size-full is-resized\"><img data-dominant-color=\"57523f\" data-has-transparency=\"false\" loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"576\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" src=\"https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides.webp\" alt=\"\" class=\"wp-image-35868 not-transparent\" style=\"--dominant-color: #57523f; width:821px;height:auto\" title=\"\" srcset=\"https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides.webp 768w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides-675x506.webp 675w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides-150x113.webp 150w\" \/><figcaption class=\"wp-element-caption\"><em><sup>AI generated image<\/sup><\/em><\/figcaption><\/figure>\n\n\n\n<p><strong>MUSCAT, Feb 23 <\/strong> \u2013 Antimicrobial resistance is intensifying as a global health threat, with few new antibiotics in the pipeline. <\/p>\n\n\n\n<p>Researchers at Sultan Qaboos University in Oman say they have identified three antimicrobial peptides (AMPs) from dromedary camels that show strong activity against multidrug-resistant bacteria, offering a potential new line of defense.<\/p>\n\n\n\n<p>The findings, published in <em>Frontiers in Immunology<\/em> on Jan. 21, detail how the team combined bioinformatics with laboratory assays, including colony-forming tests, membrane permeability studies and electron microscopy, to evaluate the peptides against strains such as MRSA and MDR <em>E. coli<\/em>.<\/p>\n\n\n\n<p>Two peptides, CdPG-3 and CdCATH, demonstrated broad-spectrum antibacterial activity, damaging bacterial membranes and causing leakage while showing low toxicity to camel and human red blood cells at lower doses.<\/p>\n\n\n\n<p>The study suggests camels\u2019 innate immunity, including cathelicidin-like AMPs, may underpin their resilience to infections common in other ruminants. \u201cThis lays the foundation for exploring camel AMPs as therapeutics against resistant pathogens,\u201d the authors wrote.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img data-dominant-color=\"ebeae3\" data-has-transparency=\"false\" loading=\"lazy\" decoding=\"async\" width=\"700\" height=\"483\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" src=\"https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/identification-of-novel-camel-antimicrobiail-peptides.webp\" alt=\"\" class=\"wp-image-35867 not-transparent\" style=\"--dominant-color: #ebeae3; width:821px;height:auto\" title=\"\" srcset=\"https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/identification-of-novel-camel-antimicrobiail-peptides.webp 700w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/identification-of-novel-camel-antimicrobiail-peptides-675x466.webp 675w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/identification-of-novel-camel-antimicrobiail-peptides-95x65.webp 95w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/identification-of-novel-camel-antimicrobiail-peptides-150x104.webp 150w\" \/><figcaption class=\"wp-element-caption\"><em><sup>Illustration titled \u201cIdentification of Novel Camel Antimicrobial Peptides\u201d showing five steps. 1: In-Silico Identification of Antimicrobial peptides using camel genome. 2: In-Silico Characterization with structures of three peptides: CdPMAP-23, CdPG-3, and CdCATH. 3: Peptides Synthesis. 4: In-Vitro Antimicrobial Analysis showing inhibited bacterial growth. 5: In- Vitro Hemolytic Analysis showing cells indicating low hemolysis.<\/sup><\/em><\/figcaption><\/figure>\n\n\n\n<p>Unlike conventional antibiotics, which often face resistance through target mutations, AMPs act by disrupting bacterial membranes, reducing the risk of adaptation. The peptides also showed low hemolytic activity, supporting their safety profile.<\/p>\n\n\n\n<p>Researchers said future work will focus on optimizing the peptides for clinical use, leveraging Oman\u2019s camel populations as a resource.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>MUSCAT, Feb 23  \u2013 Antimicrobial resistance is intensifying as a global health threat, with few new antibiotics in the pipeline.<\/p>\n","protected":false},"author":2,"featured_media":35868,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17,16],"tags":[],"class_list":["post-35866","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","category-biology"],"featured_image_urls":{"full":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides.webp",768,576,false],"thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides-200x200.webp",200,200,true],"medium":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides-675x506.webp",675,506,true],"medium_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides.webp",750,563,false],"large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides.webp",750,563,false],"1536x1536":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides.webp",768,576,false],"2048x2048":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides.webp",768,576,false],"ultp_layout_landscape_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides.webp",768,576,false],"ultp_layout_landscape":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides-768x570.webp",768,570,true],"ultp_layout_portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides-600x576.webp",600,576,true],"ultp_layout_square":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides-600x576.webp",600,576,true],"newspaper-x-single-post":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides-760x490.webp",760,490,true],"newspaper-x-recent-post-big":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides-550x360.webp",550,360,true],"newspaper-x-recent-post-list-image":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides-95x65.webp",95,65,true],"web-stories-poster-portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides-640x576.webp",640,576,true],"web-stories-publisher-logo":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides-96x96.webp",96,96,true],"web-stories-thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2026\/02\/Novel-Camel-Antimicrobial-Peptides-150x113.webp",150,113,true]},"author_info":{"info":["RevoScience"]},"category_info":"<a href=\"https:\/\/www.revoscience.com\/en\/category\/news\/research\/\" rel=\"category tag\">Research<\/a> <a href=\"https:\/\/www.revoscience.com\/en\/category\/news\/biology\/\" rel=\"category tag\">Biology<\/a>","tag_info":"Biology","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/35866","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/comments?post=35866"}],"version-history":[{"count":1,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/35866\/revisions"}],"predecessor-version":[{"id":35869,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/35866\/revisions\/35869"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media\/35868"}],"wp:attachment":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media?parent=35866"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/categories?post=35866"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/tags?post=35866"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}