{"id":6582,"date":"2015-11-05T08:05:37","date_gmt":"2015-11-05T08:05:37","guid":{"rendered":"http:\/\/revoscience.com\/en\/?p=6582"},"modified":"2015-11-05T08:05:37","modified_gmt":"2015-11-05T08:05:37","slug":"new-startup-to-make-bacteria-based-cancer-treatments","status":"publish","type":"post","link":"https:\/\/www.revoscience.com\/en\/new-startup-to-make-bacteria-based-cancer-treatments\/","title":{"rendered":"New Startup to Make Bacteria-Based Cancer Treatments"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"color: rgb(0, 0, 0);\"><a href=\"http:\/\/revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-6583\" src=\"http:\/\/revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1-300x225.jpg\" alt=\"ddd1511_bacteria (1)\" width=\"300\" height=\"225\" title=\"\" srcset=\"https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1-300x225.jpg 300w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg 500w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a>A company called Evelo Therapeutics\u00a0launched a plan to create a variety of cancer treatments based on bacteria found in the microbiome. The microbiome is an environment consisting of trillions of micro-organisms living in the body that contributes to overall health.\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: rgb(0, 0, 0);\">Evelo, located in Cambridge, Massachusetts, received $35 million in funding from the venture capital firm Flagship Ventures to study oncobiotic therapeutics. \u00a0The startup will explore what role these microbial agents play in the formation of cancer,\u00a0according to\u00a0Fierce Biotech<em>.<\/em><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: rgb(0, 0, 0);\">Evelo\u2019s approach could take a couple different forms,\u00a0reports\u00a0Stat News<em>.\u00a0<\/em><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: rgb(0, 0, 0);\">One avenue would be to test how specific kinds of bacteria inhibit tumor metabolism by competing for nutrients. Another approach would use bacterial infusions to transform a tumor\u2019s immediate surroundings into a less hospitable environment for growth.\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\">[pullquote]Harvard epidemiologist Bill Hanage expressed skepticism to the publication of the likelihood of \u201ctrying to manipulate the big and complicated immune system by using the big and complicated microbiome.\u201d[\/pullquote]<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: rgb(0, 0, 0);\">A third tactic being considered by Evelo would gage how bacteria triggers the immune system to attack tumor cells.\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: rgb(0, 0, 0);\">Microbiome research over the past several years has typically found solutions for gut diseases, like fending off infection from Clostridium difficile bug,\u00a0writes\u00a0<em>Xconomy.<\/em><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: rgb(0, 0, 0);\">However,\u00a0<em>Stat News<\/em>\u00a0notes that the science behind the microbiome is still complex and that manufacturing cancer therapies may be more difficult than it seems.\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: rgb(0, 0, 0);\">Harvard epidemiologist Bill Hanage expressed skepticism to the publication of the likelihood of \u201ctrying to manipulate the big and complicated immune system by using the big and complicated microbiome.\u201d<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: rgb(0, 0, 0);\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A company called Evelo Therapeutics launched a plan to create a variety of cancer treatments based on bacteria found in the microbiome.<\/p>\n","protected":false},"author":6,"featured_media":6583,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[],"class_list":["post-6582","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research"],"featured_image_urls":{"full":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",500,375,false],"thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1-150x150.jpg",150,150,true],"medium":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1-300x225.jpg",300,225,true],"medium_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",500,375,false],"large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",500,375,false],"1536x1536":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",500,375,false],"2048x2048":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",500,375,false],"ultp_layout_landscape_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",500,375,false],"ultp_layout_landscape":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",500,375,false],"ultp_layout_portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",500,375,false],"ultp_layout_square":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",500,375,false],"newspaper-x-single-post":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",500,375,false],"newspaper-x-recent-post-big":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",480,360,false],"newspaper-x-recent-post-list-image":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",87,65,false],"web-stories-poster-portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",500,375,false],"web-stories-publisher-logo":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",96,72,false],"web-stories-thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2015\/11\/ddd1511_bacteria-1.jpg",150,113,false]},"author_info":{"info":["Amrita Tuladhar"]},"category_info":"<a href=\"https:\/\/www.revoscience.com\/en\/category\/news\/research\/\" rel=\"category tag\">Research<\/a>","tag_info":"Research","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/6582","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/comments?post=6582"}],"version-history":[{"count":0,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/6582\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media\/6583"}],"wp:attachment":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media?parent=6582"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/categories?post=6582"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/tags?post=6582"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}