{"id":7194,"date":"2016-01-08T06:08:40","date_gmt":"2016-01-08T06:08:40","guid":{"rendered":"http:\/\/revoscience.com\/en\/?p=7194"},"modified":"2016-01-08T06:08:40","modified_gmt":"2016-01-08T06:08:40","slug":"high-dose-of-vitamin-d-could-help-people-having-multiple-sclerosis","status":"publish","type":"post","link":"https:\/\/www.revoscience.com\/en\/high-dose-of-vitamin-d-could-help-people-having-multiple-sclerosis\/","title":{"rendered":"High Dose of Vitamin D could help people having multiple sclerosis"},"content":{"rendered":"

\"shutterstock_188247899(1)\"<\/a>New research says a high dose of vitamin D is safe and may be beneficial for patients with multiple sclerosis (MS).<\/span><\/p>\n

\u201cThese results are exciting, as vitamin D has the potential to be an inexpensive, safe, and convenient treatment for people with MS,\u201d study author Peter A. Calabresi, M.D. of Johns Hopkins University said in a prepared statement. \u201cMore research is needed to confirm these findings with larger groups of people and to help us understand the mechanisms for these effects, but the results are promising.\u201d<\/span><\/p>\n

The study, published online Dec. 30 in\u00a0Neurology<\/em><\/span><\/a>, looked at 40 people with relapsing-remitting MS.\u00a0 Participants either received a high dose of 10,400 IU vitamin D supplements per day, or a lower dose of 800 IU per day for six months.\u00a0According to the Mayo Clinic<\/span><\/a>, the current recommended daily allowance for vitamin D for people aged 1 to 70 years is 600 IU.<\/span><\/p>\n

According to the study, a dose of vitamin D3 may fix the body\u2019s hyperactive immune response.\u00a0<\/span><\/p>\n

[pullquote]The target level of vitamin D needed to reduce disease activity in MS may be above 50 ng\/ml, researchers noted.[\/pullquote]<\/p>\n

Researchers tested participant\u2019s blood three times to check the response in the immune system\u2019s T cells and the amount of vitamin D in the blood.\u00a0 Blood tests were administered at the beginning of the study and again after three and six months.\u00a0 The body\u2019s T cell response plays an important role in MS.<\/span><\/p>\n

The percentage of T cells related to MS activity was reduced in people taking the high dose, while participants taking the low dose saw no changes in T cells.\u00a0 According to a press release, when the increase in vitamin D in the blood was greater than 18 nanograms per milliliter (ng\/ml), every 5 ng\/ml increase in vitamin D led to a 1 percent decrease in the percentage of interleukin 17 T cells in the blood.<\/span><\/p>\n

The target level of vitamin D needed to reduce disease activity in MS may be above 50 ng\/ml, researchers noted.\u00a0 Participants taking the higher dose reached that target level, but those taking the low dose did not.\u00a0 For the general population, vitamin D levels above 30 ng\/ml are considered sufficient.<\/span><\/p>\n

There were no major side effects from the vitamin D3 supplements and side effects did not differ between the two groups.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

New research says a high dose of vitamin D is safe and may be beneficial for patients with multiple sclerosis (MS).<\/p>\n","protected":false},"author":6,"featured_media":7195,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26,17],"tags":[],"class_list":["post-7194","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicine","category-research"],"featured_image_urls":{"full":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",500,332,false],"thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991-150x150.jpg",150,150,true],"medium":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991-300x199.jpg",300,199,true],"medium_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",500,332,false],"large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",500,332,false],"1536x1536":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",500,332,false],"2048x2048":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",500,332,false],"ultp_layout_landscape_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",500,332,false],"ultp_layout_landscape":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",500,332,false],"ultp_layout_portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",500,332,false],"ultp_layout_square":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",500,332,false],"newspaper-x-single-post":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",500,332,false],"newspaper-x-recent-post-big":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",500,332,false],"newspaper-x-recent-post-list-image":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",95,63,false],"web-stories-poster-portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",500,332,false],"web-stories-publisher-logo":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",96,64,false],"web-stories-thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/01\/shutterstock_1882478991.jpg",150,100,false]},"author_info":{"info":["Amrita Tuladhar"]},"category_info":"Medicine<\/a> Research<\/a>","tag_info":"Research","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/7194","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/comments?post=7194"}],"version-history":[{"count":0,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/7194\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media\/7195"}],"wp:attachment":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media?parent=7194"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/categories?post=7194"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/tags?post=7194"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}