{"id":8609,"date":"2016-04-27T09:41:36","date_gmt":"2016-04-27T09:41:36","guid":{"rendered":"http:\/\/revoscience.com\/en\/?p=8609"},"modified":"2016-04-27T09:41:36","modified_gmt":"2016-04-27T09:41:36","slug":"new-rd-pact-seeks-cure-for-aging-related-diseases","status":"publish","type":"post","link":"https:\/\/www.revoscience.com\/en\/new-rd-pact-seeks-cure-for-aging-related-diseases\/","title":{"rendered":"New R&#038;D Pact Seeks Cure for Aging-Related Diseases"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"color: #000000;\"><a href=\"http:\/\/revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-8617\" src=\"http:\/\/revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech-300x199.jpg\" alt=\"ddd1604_biotech\" width=\"300\" height=\"199\" title=\"\" srcset=\"https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech-300x199.jpg 300w, https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg 420w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a>Google\u2019s Calico, an institution with a mysterious mission to \u201ccure death\u201d could have competition from a new collaboration struck between Ascentage Pharma and Unity Biotechnology.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">A joint\u00a0<a style=\"color: #bf3b41;\" href=\"http:\/\/www.prnewswire.com\/news-releases\/ascentage-pharma-and-unity-biotechnology-announce-collaboration-for-the-development-of-senolytic-healthspan-therapies-300256473.html\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #000000;\">statement<\/span><\/a>\u00a0released by both firms explained this new agreement will focus on developing new medications to improve health span. The specific goal will be developing senolytic treatments, which are small-molecule therapies that target senescent cells.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">These cells \u201cbuild up with age and after genotoxic stress, such as total-body irradiation,\u201d\u00a0<a style=\"color: #bf3b41;\" href=\"http:\/\/www.fiercebiotech.com\/biotech\/ascentage-pharma-unity-biotech-collab-to-cure-old-age\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #000000;\"><em>wrote FierceBiotech.<\/em><\/span><\/a>\u00a0The publication cited recent research published in\u00a0<em>Nature<\/em>\u00a0that shows clearing out these cells in a mouse model delayed numerous age-associated disorders.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">Kidney disease, glaucoma, and atherosclerosis were some of the diseases Unity cited as responding well to these treatments.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">Details surrounding this undertaking are sparse, but\u00a0<em>FierceBiotech\u00a0<\/em>added that both firms will create a joint venture for the development and commercialization of these drugs in China where Ascentage is based.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">Calico, however, is still tightlipped about its own plans. The organization formed back in 2013 with great fanfare with the intended goal of pursuing medical breakthroughs that could prolong the human lifespan.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">Calico struck a $500 million joint\u00a0<a style=\"color: #bf3b41;\" href=\"http:\/\/www.dddmag.com\/news\/2014\/09\/googles-health-startup-forges-venture-abbvie?\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #000000;\">partnership<\/span><\/a>\u00a0with AbbVie in 2014 to identify new treatment methods for Alzheimer\u2019s and cancer. Another collaboration followed in March 2015 when Calico<a style=\"color: #bf3b41;\" href=\"http:\/\/www.dddmag.com\/articles\/2015\/03\/google-teams-mit-harvard-genetics-research-project\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #000000;\">announced<\/span><\/a>\u00a0it would collaborate with The Broad Institute to analyze aging-related diseases.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A joint statement released by both firms explained this new agreement will focus on developing new medications to improve health span.<\/p>\n","protected":false},"author":6,"featured_media":8617,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[17],"tags":[],"class_list":["post-8609","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research"],"featured_image_urls":{"full":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",420,279,false],"thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech-150x150.jpg",150,150,true],"medium":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech-300x199.jpg",300,199,true],"medium_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",420,279,false],"large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",420,279,false],"1536x1536":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",420,279,false],"2048x2048":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",420,279,false],"ultp_layout_landscape_large":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",420,279,false],"ultp_layout_landscape":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",420,279,false],"ultp_layout_portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",420,279,false],"ultp_layout_square":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",420,279,false],"newspaper-x-single-post":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",420,279,false],"newspaper-x-recent-post-big":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",420,279,false],"newspaper-x-recent-post-list-image":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",95,63,false],"web-stories-poster-portrait":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",420,279,false],"web-stories-publisher-logo":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",96,64,false],"web-stories-thumbnail":["https:\/\/www.revoscience.com\/en\/wp-content\/uploads\/2016\/04\/ddd1604_biotech.jpg",150,100,false]},"author_info":{"info":["Amrita Tuladhar"]},"category_info":"<a href=\"https:\/\/www.revoscience.com\/en\/category\/news\/research\/\" rel=\"category tag\">Research<\/a>","tag_info":"Research","comment_count":"0","_links":{"self":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/8609","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/comments?post=8609"}],"version-history":[{"count":0,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/posts\/8609\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media\/8617"}],"wp:attachment":[{"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/media?parent=8609"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/categories?post=8609"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.revoscience.com\/en\/wp-json\/wp\/v2\/tags?post=8609"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}